The second part of Story 3 explores more aspects of the DNA molecule both when used as a message and when used to create new organisms. Also, we take a look into biological processes that are defined in terms of positive and negative feedback loops.Here are some questions you might want to discuss with your kids:

Q: What happens when we change a sequence in the DNA or we start messing with the DNA strand and we cut and paste pieces from other DNA strands into it?
A: We get an engineered DNA strand that may or may not exist in nature. The change can be as small as changing the color of your hair or as big as transforming you into a new type of organism altogether, like a mutant.

Q: What do you think is Daena’s best quality that makes her a great DNA detective?
A: First, she knows her biology. Second, she is inventive and tries to find solutions based on her knowledge. Third, her solutions are not complicated. They are simple and they work.

Q: How did Daena beat the Ugga Ugga virus at the end?
A: First she changed the DNA of the Ugga Ugga virus to create a stronger (and not evil) virus, the Gaga Gaga virus, and then used the Gaga Gaga virus to kill the Ugga Ugga virus by creating a negative-positive feedback loop.

Q: How does a negative feedback loop work? Can you show an example of a negative feedback loop at your home?
A: A negative feedback loop works by regulating the amount of something. The more of the “something” we have, the feedback loop will try to make this “something” less. The less of the “something” we have, the feedback loop will try to make this “something” more.
This is for example how we maintain temperature in a house using a thermostat. In this case the “something” is the “heat”. The more heat we have, the thermostat will tell the A/C to blow cool air into the house to bring down the heat.

I hope we learned something useful today,
Dr. Techniko